Explant Methodology for Analyzing Neuroblast Migration

Explant Methodology for Analyzing Neuroblast Migration

Blog Article

The Non Electric Pendant subventricular zone (SVZ) in the mammalian forebrain contains stem/progenitor cells that migrate through the rostral migratory stream (RMS) to the olfactory bulb throughout adulthood.SVZ-derived explant cultures provide a convenient method to assess factors regulating the intermediary stage of neural stem/progenitor cell migration.Here, we describe the isolation of SVZ-derived RMS explants from the Used Goal Pants neonatal mouse brain, and the conditions required to culture and evaluate their migration.